Adolescent rats enjoy cannabis more than their elders

2019-03-02 05:03:08

Adolescent rats are more likely than adults to be attracted by cannabis – and seem more susceptible to the drug’s effects on memory. Over a period of 18 days, Iain McGregor at the University of Sydney, Australia, and colleagues injected rats with tetrahydrocannabinol (THC), the active ingredient in cannabis, at doses designed to mimic heavy cannabis use in humans. Two weeks after the final dose, the adult rats avoided the regions of the testing chamber where they had received injections, but the adolescents showed no such aversion. This suggests that the adult rats found the THC unpleasant, while the adolescents didn’t,